Agent


The AGENT™ Paclitaxel Drug Coated Balloon catheter, with its innovative TransPax™ coating technology1, provides a targeted, therapeutic dose of proven, anti-proliferative Paclitaxel to the lesion2. It was designed to minimise downstream particulates while maintaining the outstanding deliverability you’ve come to expect with Boston Scientific products.

Optimal dose of 2µg/mm2 compared to 3µg/mm2 of market leading DCBs efficiently achieves sustained benefits of Paclitaxel2 over time.

Optimized Drug Transfer

  • TransPaxTM coating ensures targeted delivery of Paclitaxel†
  • Optimal dose of 2 μg/mm2 compared to 3 μg/mm2 of market leading DCBs‡

Outstanding Deliverability5

  • AgentTM DCB offers exceptional deliverability leveraging the EMERGETM PTCA Catheter:
  • Designed to navigate and cross challenging lesions
    • Ultra-low tip profile
    • Bi-segment inner shaft: flexible distal segment and pushable  proximal segment.

Enhanced Coating Integrity

  • Balanced hydrophobic and hydrophilic properties of Trans PaxTM coating ensures balloon reaches the lesion with the optimal amount of drug for your patient.
  • Fewer particulates are lost distally during the procedure

Agent Infographic

History

History for Paclitaxel on cardiovascular space

How it works*

Once the DCB has been deployed, the durable TransPax coating:

1. Ensures that a consistent drug dose is delivered to a lesion*

2. Binds with microtubules to inhibit proliferation of smooth-muscle cells*

3. Enables healing by selectively impacting cells that cause restenosis while allowing healing of endothelial cells*

Infographic of TransPax Coating Technology

Safety and performance*

Enhanced Coating Integrity

Enhanced Coating Integrity*

Designed to improve coating durability and drug transfer efficacy, allowing for a lower dosage of Paclitaxel*

Optimized Drug Transfer

Optimized Drug Transfer°

Balanced hydrophobic and hydrophilic properties allow efficient drug transfer to the vessel wall

Minimized Systemic Loss

Minimized Systemic Loss

Less particulates and systemic loss while optimizing arterial tissue Paclitaxel levels.

https://www.youtube.com/watch?v=SvLuQBlnHpg